deep or great sorrow
mental suffering
Cases of word usage
1) to make (a person) mad (because of worry, grief etc) (derange)
2) to suffer grief (because of a person, thing) (grieve)
3) an expression of grief; a song or poem expressing grief (lament)
4) (the wearing of) black clothes as a sign of grief (mourning)
5) (a cause of) trouble, grief (tribulation)