(an example of) worry; unhappiness; difficulty; a nuisance; (an) illness
annoyance, worry
Cases of word usage
1) (an instance of) bad luck, trouble (adversity)
2) (usually passive) to attack, cause trouble for, (a person, business etc) in several ways (beset)
3) suitable; that avoids trouble or difficulty (convenient)
4) daring, mischievous or adventurous act, often one causing gossip or trouble (escapade)
5) very wicked, bad; likely to cause trouble (evil)
6) a feeling that trouble is coming (foreboding)
7) (a cause or instance of) discomfort or trouble (inconvenience)
8) causing discomfort, trouble or annoyance (inconvenient)
9) a disorganized crowd, especially one that has gathered to make trouble or attack; a gang of criminals (mob)
10) to trouble or annoy (a person) intentionally, especially making sexual attacks (molest)