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Meaning:
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unhappiness, depression

unhappiness, depression

anguish grief heartache heartbreak hopelessness melancholy misery mourning poignancy sorrow blahs bleakness bummer cheerlessness dejection despondency disconsolateness dispiritedness distress dolefulness dolor downer dysphoria forlornness funk gloominess letdown listlessness moodiness mopes mournfulness sorrowfulness tribulation woe blue devils blue funk broken heart dismals downcastness grieving heavy heart the blues the dumps
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Cases of word usage

1) feeling great sadness especially because of unfair treatment (aggrieved)

2) (of a person) made to feel sympathy, sadness etc (moved)

3) causing pity and sadness (poignant)

4) to think of (something) with sadness or regret (rue)

5) (a) mental feeling of love, happiness, pity, sadness etc; an opinion or judgement (sentiment)

6) (a cause of) sadness or regret (sorrow)

SADNESS as in Wiktionary
SADNESS as in Wikipedia