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1) a very strong headache (migraine)

Synonyms
UK
US
Meaning:
bore

a person who people find uninteresting and tiring

nuisance

bother

a person, thing, that causes trouble, worry or annoyance

trouble, inconvenience

distress

(a cause of) great pain, discomfort or sorrow

pain, agony

hangover

an unpleasant feeling after a period of drinking alcohol

result of heavy drinking

migraine

a very strong headache

serious headache

misery

the state of being very unhappy; great suffering (of mind or body); great misfortune

pain, mental or physical

nuisance

a person, insect, thing, act etc that causes trouble or offence

annoyance; annoying person

onerous

needing much effort

difficult; requiring hard labor

pest

a troublesome or destructive thing, animal etc; a child who is a nuisance

person or thing that presents problem

problem

a question to be solved or decided, especially something difficult

difficulty; bad situation

task

a particular piece of work (to be) done

job or chore, often assigned

tormentor

a person who torments

person or thing that presents problem

tribulation

(a cause of) trouble, grief

pain, unhappiness

woes

suffering

suffering

woe

great sadness; causes of woe; troubles

suffering

worry

(something that causes) the state feeling anxious or troubled

anxiety, trouble

HEADACHE as in Wiktionary
HEADACHE as in Wikipedia