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Meaning:
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(of meat) hard to cut or get one's teeth into; not easily cut, broken or worn out; (of a person) strong; able to endure hardship; (of a person) rough and violent

sturdy, strong

hard healthy resilient solid stiff tenacious tight vigorous firm fit hardy stalwart stout brawny cohesive conditioned dense durable fibrous flinty hard as nails hard-bitten hardened indigestible inflexible leathery lusty mighty molded resistant rigid robust rugged seasoned sinewy steeled strapping tough as nails unbreakable unyielding withstanding
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Cases of word usage

1) the light, brown, tough outer bark of a kind of tree (called the cork-oak) (cork)

2) (to cause a person, meat) to become tough (toughen)

TOUGH as in Wiktionary
TOUGH as in Wikipedia 
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