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Meaning:
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a mark, object, symbol etc used to represent something: 'mathematical sings' such as '+', '-', 'x', '?'; a word or words, design etc on a board or plate to give a warning, or to give direction; to write (one's name) on (a letter, application form etc)

indication, evidence

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Cases of word usage

1) the Water Carrier, the eleventh sign of the zodiac (Aquarius)

2) to be a sign that something will develop badly or well (augur)

3) to suggest, be a sign of, failure or success (bode)

4) (of a woman or girl) a formal sign of respect (by bending one or both knees) (e.g. to a queen) (curtsy)

5) to take (a person) in one's arms, as a sign of affection (embrace)

6) a statement of equality between two expressions by using the sign ( = ), as in 2x + 5 = 11 (equation)

7) a condition of the human body with a temperature higher than usual, especially when a sign of illness (fever)

8) a sign of what is to follow; a person who prepares for the coming of another person or thing (forerunner)

9) to be a sign or warning of (something bad) (foreshadow)

10) the third sign of the zodiac (gemini)

SIGN as in Wiktionary
SIGN as in Wikipedia