Cases of word usage

1) to make (something) worse or more serious (aggravate)

2) a serious and determined request (appeal)

3) a big and serious misfortune or disaster (e.g. an earthquake or flood) (calamity)

4) serious attention or effort (care)

5) (of efforts, hopes, careers etc) to reach the highest or most serious point (culminate)

6) (especially of a woman) quiet and serious (demure)

7) (of a person, action) showing a serious wish to do something successfully (determined)

8) paying serious attention to religious duties (devout)

9) (a) large or sudden misfortune (e.g. a flood or fire, an earthquake, a serious defeat in war, the loss of a large sum of money) (disaster)

10) (of a person's character, expression) gloomy, serious and unfriendly (dour)