1) a hard, painful and poisoned swelling under the skin (boil)
2) a sudden and painful tightening of the muscles, usually caused by cold or overwork, making movement difficult (cramp)
3) strong, cold and painful (cutting)
4) a painful disease of the bowels which produces mucus and blood (dysentery)
5) the painless killing of people suffering from incurable painful diseases (euthanasia)
6) a disease causing painful swellings in joints, especially toes, knees and fingers (gout)
7) that cannot be tolerated because too strong, painful etc (intolerable)
8) any severe or painful test of character or endurance (ordeal)
9) a painful squeeze using the fingers and thumb; an amount which can be taken up with the thumb finger (pinch)
10) (of smells, tastes) very strong, sharp; (of remarks) very painful (pungent)
needing and using much energy and thought
difficult, hard to endure
(of a person) taking pleasure in causing pain to, watching the suffering of, others
vicious, pitiless; causing pain
requiring much effort, strength, skill or ability
hard on someone; hard to do
sad, depressed
depressing
causing distress
dangerous, frightening
unbearable
horrible, intolerable
that cannot be tolerated because too strong, painful etc
unacceptable; beyond bearing
needing much effort
difficult; requiring hard labor
(of a part of the body) painful; hurting when touched or used; filled with sorrow; sad
hurt physically
of tragedy; very sad or unfortunate
catastrophic, very bad
causing worry, unhappiness, difficulty
bothersome, worrisome
(moving) in the opposite direction to the stream or current
hard on someone; hard to do