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1) a large-scale destruction, especially of human lives (holocaust)

Synonyms
UK
US
Meaning:
catholic

general; including many or most things

all-embracing, general

considerable

large in amount, importance etc

abundant, large

extensive

large in area, amount, degree etc

far-reaching, thorough

hefty

big, strong

big, bulky

major

greatest or more important (than others)

bigger

masser

all-inclusive

all-inclusive

outspread

spread or stretched out

expansive, roomy

wholesale

concerning selling in large amounts (especially to shops etc); on a large scale

all-inclusive

wide

measuring much from side to side; large, unlimited; of great extent

expansive, roomy

LARGE-SCALE as in Wiktionary
LARGE-SCALE as in Wikipedia