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1) unhelpful or hurtful (adverse)

Synonyms
UK
US
Meaning:
abrasive

causing an abrasion

irritating in manner

cutting

strong, cold and painful

nasty, hateful

destructive

causing destruction; fond of, in the habit of, destroying

injurious, devastating

grievous

severe

severe, painful; serious

lethal

causing, able to cause, death

deadly

mischievous

filled with, engaged in, mischief

devilish, wicked

noxious

harmful

deadly, injurious

poisonous

having poison; causing death or injury

harmful

ruinous

causing ruin

disastrous, devastating

septic

causing, caused by infection (with disease germs)

harmful

sinister

suggesting evil or the likelihood of bad luck

nasty, menacing

snide

sneering; suggesting unpleasant thoughts

hateful, nasty

sore

(of a part of the body) painful; hurting when touched or used; filled with sorrow; sad

hurt physically

HURTFUL as in Wiktionary
HURTFUL as in Wikipedia