1) unhelpful or hurtful (adverse)
causing an abrasion
irritating in manner
strong, cold and painful
nasty, hateful
causing destruction; fond of, in the habit of, destroying
injurious, devastating
severe
severe, painful; serious
causing, able to cause, death
deadly
filled with, engaged in, mischief
devilish, wicked
harmful
deadly, injurious
having poison; causing death or injury
harmful
causing ruin
disastrous, devastating
causing, caused by infection (with disease germs)
harmful
suggesting evil or the likelihood of bad luck
nasty, menacing
sneering; suggesting unpleasant thoughts
hateful, nasty
(of a part of the body) painful; hurting when touched or used; filled with sorrow; sad
hurt physically