1) of which the effect cannot at that point be judged as important or not, or cannot be estimated (imponderable)
2) too great, precious et to be estimated (inestimable)
3) an empty space round writing or printing on a page; an edge or border; an amount (of time, money etc) above what is estimated as necessary (margin)
deliberately planned
figured by mathematical calculations
generally considered or reported (to be); generally considered to be (but with some doubt)
believed
a form of medicine in a container (to be) put into the rectum or vagina
believed