something that adds new difficulties (e.g. of a person who is ill)

difficult situation

(an example, instance, of) being intricate

complication

a confused state

confused state

a question, statement or description, intended to make a person think hard in order to know the answer or meaning; to make many holes in a person, thing

brain-teaser

(of an animal) (to make) a sound, act, of growling with the teeth showing; (of a person) (to speak in) a low, angry voice; a confused state; a knot, tangle (in wool etc)

complication, mess

a net made of threads by a spider; an arrangement as a trap or barrier; the internet; the world wide web

netting